Drug Information

Drug General Information
Drug ID
D09NNI
Former ID
DNC011819
Drug Name
3-Methoxy-9H-beta-carboline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533363]
Formula
C12H10N2O
Canonical SMILES
COC1=NC=C2C(=C1)C3=CC=CC=C3N2
InChI
1S/C12H10N2O/c1-15-12-6-9-8-4-2-3-5-10(8)14-11(9)7-13-12/h2-7,14H,1H3
InChIKey
UFGGNIMGPVLCJZ-UHFFFAOYSA-N
PubChem Compound ID
363113
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Inhibitor [533363]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533363]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533363J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
Ref 533363J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.

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