Drug Information

Drug General Information
Drug ID
D09JYF
Former ID
DIB011945
Drug Name
Epocarbazolin-A
Synonyms
Epocarbazolin-B
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [534037]
Company
Bristol-Myers Squibb Co
Formula
C22H27NO4
Canonical SMILES
C1(OC1(CCC(C)C)C)c1c2[nH]c3c(c2cc(c1C)O)c(ccc3O)CO
CAS Number
CAS 146935-39-9
PubChem Compound ID
192365
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [534037]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 534037Epocarbazolins A and B, novel 5-lipoxygenase inhibitors. Taxonomy, fermentation, isolation, structures and biological activities. J Antibiot (Tokyo). 1993 Jan;46(1):25-33.
Ref 534037Epocarbazolins A and B, novel 5-lipoxygenase inhibitors. Taxonomy, fermentation, isolation, structures and biological activities. J Antibiot (Tokyo). 1993 Jan;46(1):25-33.

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