Drug Information

Drug General Information
Drug ID
D09GQF
Former ID
DNC009272
Drug Name
5,N-Dihydroxythalidomide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529568]
Formula
C13H10N2O6
Canonical SMILES
C1CC(=O)N(C(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)O)O
InChI
1S/C13H10N2O6/c16-6-1-2-7-8(5-6)12(19)14(11(7)18)9-3-4-10(17)15(21)13(9)20/h1-2,5,9,16,21H,3-4H2
InChIKey
RLBGOICZNMULCW-UHFFFAOYSA-N
PubChem Compound ID
10356851
Target and Pathway
Target(s) Progesterone receptor Target Info Inhibitor [529568]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturation
Pathway Interaction Database Cellular roles of Anthrax toxin
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathway
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear Receptors
References
Ref 529568Bioorg Med Chem. 2008 Jul 15;16(14):7046-54. Epub 2008 May 10.Progesterone receptor antagonists with a 3-phenylquinazoline-2,4-dione/2-phenylisoquinoline-1,3-dione skeleton.
Ref 529568Bioorg Med Chem. 2008 Jul 15;16(14):7046-54. Epub 2008 May 10.Progesterone receptor antagonists with a 3-phenylquinazoline-2,4-dione/2-phenylisoquinoline-1,3-dione skeleton.

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