Drug Information

Drug General Information
Drug ID
D09DSK
Former ID
DIB011206
Drug Name
JWH-051
Synonyms
CB2 receptor agonists (pain); CB2 receptor agonists (pain), Merck
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Investigative [543878]
Company
Merck & Co Inc
Canonical SMILES
c1([C@@]2(O)[C@@H]3CCCC[C@@H]3N(CC2)C(=O)c2cnc(cc2)C)cc<br />ccc1
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Agonist [543878]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543878(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).
Ref 543878(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).

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