Drug Information

Drug General Information
Drug ID
D09CQO
Former ID
DNC012024
Drug Name
2-Thiophen-2-yl-3H-imidazo[4,5-c]quinoline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534155]
Formula
C14H9N3S
Canonical SMILES
C1=CC=C2C(=C1)C3=C(C=N2)NC(=N3)C4=CC=CS4
InChI
1S/C14H9N3S/c1-2-5-10-9(4-1)13-11(8-15-10)16-14(17-13)12-6-3-7-18-12/h1-8H,(H,16,17)
InChIKey
APVZAVOHLAQECW-UHFFFAOYSA-N
PubChem Compound ID
10705898
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [534155]
Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [534155]
Gamma-aminobutyric acid receptor Target Info Inhibitor [534155]
Gamma-aminobutyric acid receptor subunit beta-2 Target Info Inhibitor [534155]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Serotonergic synapse
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 534155J Med Chem. 1996 Jul 5;39(14):2844-51.Synthesis and structure--activity relationships of fused imidazopyridines: a new series of benzodiazepine receptor ligands.
Ref 534155J Med Chem. 1996 Jul 5;39(14):2844-51.Synthesis and structure--activity relationships of fused imidazopyridines: a new series of benzodiazepine receptor ligands.

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