Drug Information

Drug General Information
Drug ID
D09BJW
Former ID
DNC011781
Drug Name
9-Methoxy-1,2,3,4-tetrahydro-anthracen-2-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551246]
Formula
C15H17NO
Canonical SMILES
COC1=C2CC(CCC2=CC3=CC=CC=C31)N
InChI
1S/C15H17NO/c1-17-15-13-5-3-2-4-10(13)8-11-6-7-12(16)9-14(11)15/h2-5,8,12H,6-7,9,16H2,1H3
InChIKey
XZOPIEFNQZTGHL-UHFFFAOYSA-N
PubChem Compound ID
10775682
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [551246]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 551246Synthesis of new derivatives of 8-OH-DPAT: Influence of substitution on the aromatic ring on the pharmacological profile, Bioorg. Med. Chem. Lett. 3(10):2035-2038 (1993).
Ref 551246Synthesis of new derivatives of 8-OH-DPAT: Influence of substitution on the aromatic ring on the pharmacological profile, Bioorg. Med. Chem. Lett. 3(10):2035-2038 (1993).

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