Drug Information

Drug General Information
Drug ID
D08QRO
Former ID
DIB007291
Drug Name
BL-6020
Synonyms
SNT-207707; SNT-207858; SNT-209858; MC4-R antagonists (anorexia), Santhera; MC4-R antagonists (cachexia), Santhera; Melanocortin 4 receptor antagonists (cachexia/anorexia), Santhera; MC4-R antagonists (cachexia/anorexia), Santhera; MC4-R antagonists (cachexia/anorexia), Santhera/ BioLineRx
Indication Cachexia [ICD9: 799.4; ICD10:R64] Investigative [543735]
Company
MyoContract Pharmaceutical Research Ltd
Canonical SMILES
Cl.Cl.C1CN(CC1)CCCc1n2cc(C(=O)N(CCC(C)C)CCC(C)C)ccc2nc1<br />c1ccc(cc1)C#N
Target and Pathway
Target(s) Melanocortin-4 receptor Target Info Antagonist [543735]
KEGG Pathway Neuroactive ligand-receptor interaction
Pathway Interaction Database Syndecan-3-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (s) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543735(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 285).
Ref 543735(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 285).

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