Drug Information

Drug General Information
Drug ID
D08OKJ
Former ID
DAP001312
Drug Name
Iron Dextran
Synonyms
Chinofer; Dexferrum; Dextrofer; Eisendextran; Fenate; Ferridextran; Ferrodextran; Ferroglucin; Hematran; Icar; Imfergen; Imferon; Imperon; Imposil; Infed; Iron; Norferan; Polyfer; Proferdex; Prolongal; Ursoferran; Dextran iron complex; Eisendextran [German]; Fero Gradumet; Ferric dextran; Iron dextran complex; Iron dextran injection; Iron hydrogenated dextran; Ironorm injection; Sulfuric acid; A 100; B 75; Dextrofer 75; Ferdex 100; Ferroglukin 75; Myofer 100; A 100 (Pharmaceutical); American Regent Brand of Iron-Dextran Complex; Dextran-Iron Complex; Fe-Dextran; GlaxoSmithKline Brand of Iron-Dextran Complex; Goldline Brand of Iron-Dextran Complex; Hauck Brand of Iron-Dextran Complex; Hawthron Brand of Iron-Dextran Complex; Iro-Jex; Iron-dextran complex; Sanofi Brand of Iron-Dextran Complex; Sulfuric acid, iron salt; Sulphuric acid, iron salt; Vortech Brand of Iron-Dextran Complex; Watson Brand of Iron-Dextran Complex; Sulfuric acid iron salt (1:1); Sulfuric acid, iron salt (1:); Sulfuric acid iron(2+) salt (1:1)
Drug Type
Small molecular drug
Indication Iron deficiency anaemia [ICD10:D50] Approved [538437], [551871]
Therapeutic Class
Iron Supplement
Formula
FeH2O4S
Canonical SMILES
OS(=O)(=O)O.[Fe]
InChI
1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)
InChIKey
MVZXTUSAYBWAAM-UHFFFAOYSA-N
CAS Number
CAS 9004-66-4
PubChem Compound ID
105075
PubChem Substance ID
548379, 559816, 10626730, 11035380, 14747944, 44434606, 53789165, 57338002, 57406360, 77043282, 103825399, 104373571, 109769168, 126430876, 126673763, 135061941, 137002937, 162179161, 163135263, 164808513, 176259451
SuperDrug ATC ID
B05AA05
Target and Pathway
Target(s) Hemoglobin Target Info Activator [536828]
KEGG Pathway African trypanosomiasis
Malaria
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Scavenging of heme from plasma
WikiPathways Binding and Uptake of Ligands by Scavenger Receptors
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
Factors involved in megakaryocyte development and platelet production
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 538437FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 010787.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536828Efficacy and safety of total dose infusion of low molecular weight iron dextran in the treatment of iron deficiency anemia during pregnancy. J Coll Physicians Surg Pak. 2008 Jul;18(7):424-7.

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