Drug Information

Drug General Information
Drug ID
D08OJF
Former ID
DCL000130
Drug Name
ICA-105665
Indication Epilepsy [ICD10:G40] Phase 2 [532366]
Company
Icagen
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily KQT member 3 Target Info Activator [536757]
KEGG Pathway Cholinergic synapse
Reactome Voltage gated Potassium channels
Interaction between L1 and Ankyrins
WikiPathways Potassium Channels
L1CAM interactions
References
Ref 532366Kv7 potassium channel activation with ICA-105665 reduces photoparoxysmal EEG responses in patients with epilepsy. Epilepsia. 2013 Aug;54(8):1437-43.
Ref 536757New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channels. Curr Neurol Neurosci Rep. 2008 Jul;8(4):345-52.

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