Drug Information

Drug General Information
Drug ID
D08OCL
Former ID
DNC014610
Drug Name
4-(5-Nitro-indol-1-ylmethyl)-benzamidine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533527]
Formula
C16H14N4O2
Canonical SMILES
C1=CC(=CC=C1CN2C=CC3=C2C=CC(=C3)[N+](=O)[O-])C(=N)N
InChI
1S/C16H14N4O2/c17-16(18)12-3-1-11(2-4-12)10-19-8-7-13-9-14(20(21)22)5-6-15(13)19/h1-9H,10H2,(H3,17,18)
InChIKey
TYZQZZRAPZQXLG-UHFFFAOYSA-N
PubChem Compound ID
44331823
Target and Pathway
Target(s) Trypsin Target Info Inhibitor [533527]
KEGG Pathway Neuroactive ligand-receptor interaction
Pancreatic secretion
Protein digestion and absorption
Influenza A
Reactome Activation of Matrix Metalloproteinases
Cobalamin (Cbl, vitamin B12) transport and metabolism
WikiPathways Activation of Matrix Metalloproteinases
References
Ref 533527J Med Chem. 1983 Feb;26(2):294-8.Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin.
Ref 533527J Med Chem. 1983 Feb;26(2):294-8.Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin.

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