Drug Information

Drug General Information
Drug ID
D08LZZ
Former ID
DIB016350
Drug Name
DPO-1
Synonyms
DPO-1; IKur blockers (atrial arrythmia), Merck & Co; Kv1.5 voltage-gated potassium channel antagonists (atrial arrythmia); Kv1.5 voltage-gated potassium channel antagonists (atrial arrythmia), Merck & Co
Drug Type
Small molecular drug
Indication Atrial fibrillation [ICD9: 272, 427.31; ICD10:E78, I48] Investigative [543876]
Company
Merck & Co Inc
Formula
C22H29OP
Canonical SMILES
FC(F)(F)Cc1n(c2ncccc2CC(c2cccnc2)c2cnccc2)c2c(n1)cccc2
PubChem Compound ID
21678144
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily A member 5 Target Info Antagonist [543876]
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channels
WikiPathways Potassium Channels
References
Ref 543876(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 542).
Ref 543876(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 542).

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