TTD | Drug: D08KPQ

Drug General Information
Drug ID	D08KPQ
Former ID	DIB020303
Drug Name	M8-B
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541515]
Formula	C22H24N2O3S
InChI	InChI=1S/C22H24N2O3S/c1-26-20-14-18(9-10-19(20)27-16-17-6-3-2-4-7-17)15-24(12-11-23)22(25)21-8-5-13-28-21/h2-10,13-14H,11-12,15-16,23H2,1H3
InChIKey	UOGGWHBYFVBUIY-UHFFFAOYSA-N
PubChem Compound ID	11675630
PubChem Substance ID	16779649, 23773148, 42842567, 74504861, 141768224, 174509776, 178102994, 239064855, 248003417
Target and Pathway
Target(s)	TRPM8 protein	Target Info	Blocker (channel blocker)	[531795]
KEGG Pathway	Inflammatory mediator regulation of TRP channels
Reactome	TRP channels
References
Ref 541515	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6376).
Ref 531795	Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature. J Neurosci. 2012 Feb 8;32(6):2086-99.

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Drug Information