Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08BGK
|
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| Former ID |
DIB020504
|
||||
| Drug Name |
N-chloromethyl-brucine
|
||||
| Synonyms |
N-chloromethylbrucine
|
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| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [540379] | ||
| Formula |
C24H28ClN2O4+
|
||||
| InChI |
InChI=1S/C24H28ClN2O4/c1-29-17-8-15-16(9-18(17)30-2)26-21(28)10-19-22-14-7-20-24(15,23(22)26)4-5-27(20,12-25)11-13(14)3-6-31-19/h3,8-9,14,19-20,22-23H,4-7,10-12H2,1-2H3/q+1/t14-,19-,20-,22-,23-,24+,27?/m0/s1
|
||||
| InChIKey |
GCEPQLWZBVGLQN-CQIPDZJVSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Muscarinic receptor | Target Info | Modulator (allosteric modulator) | [534573] | |
| Muscarinic acetylcholine receptor M3 | Target Info | Modulator (allosteric modulator) | [534573] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| cAMP signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| PI3K-Akt signaling pathway | |||||
| Cholinergic synapse | |||||
| Regulation of actin cytoskeletonhsa04020:Calcium signaling pathway | |||||
| Regulation of actin cytoskeleton | |||||
| Insulin secretion | |||||
| Salivary secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| PathWhiz Pathway | Muscle/Heart ContractionPW000565:Gastric Acid Production | ||||
| WikiPathways | Monoamine GPCRs | ||||
| Calcium Regulation in the Cardiac Cell | |||||
| Regulation of Actin Cytoskeleton | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Secretion of Hydrochloric Acid in Parietal Cells | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP58:Monoamine GPCRs | |||||
| Integration of energy metabolism | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
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