Drug Information

Drug General Information
Drug ID
D07XLQ
Former ID
DNC009919
Drug Name
N-{4-[2-(4-Methoxyphenyl)ethyl]phenyl}phthalimide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530220]
Formula
C23H19NO3
Canonical SMILES
COC1=CC=C(C=C1)CCC2=CC=C(C=C2)N3C(=O)C4=CC=CC=C4C3=O
InChI
1S/C23H19NO3/c1-27-19-14-10-17(11-15-19)7-6-16-8-12-18(13-9-16)24-22(25)20-4-2-3-5-21(20)23(24)26/h2-5,8-15H,6-7H2,1H3
InChIKey
CRWGIKAUSJNKIC-UHFFFAOYSA-N
PubChem Compound ID
44537911
Target and Pathway
Target(s) Oxysterols receptor LXR-alpha Target Info Inhibitor [530220]
KEGG Pathway PPAR signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hepatitis C
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptor
WikiPathways Nuclear Receptors in Lipid Metabolism and Toxicity
Nuclear Receptors Meta-Pathway
PPAR Alpha Pathway
Liver X Receptor Pathway
Adipogenesis
SREBF and miR33 in cholesterol and lipid homeostasis
Nuclear Receptors
References
Ref 530220Bioorg Med Chem. 2009 Jul 15;17(14):5001-14. Epub 2009 Jun 2.Separation of alpha-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRalpha-selective antagonists.
Ref 530220Bioorg Med Chem. 2009 Jul 15;17(14):5001-14. Epub 2009 Jun 2.Separation of alpha-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRalpha-selective antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.