Drug Information

Drug General Information
Drug ID
D07ROK
Former ID
DNC007815
Drug Name
N-(3-(1H-indol-4-yloxy)propyl)cyclopentanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529018]
Formula
C16H22N2O
Canonical SMILES
C1CCC(C1)NCCCOC2=CC=CC3=C2C=CN3
InChI
1S/C16H22N2O/c1-2-6-13(5-1)17-10-4-12-19-16-8-3-7-15-14(16)9-11-18-15/h3,7-9,11,13,17-18H,1-2,4-6,10,12H2
InChIKey
IYOLOIDWTZSJFT-UHFFFAOYSA-N
PubChem Compound ID
44433248
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [529018]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529018Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.
Ref 529018Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.

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