Drug Information

Drug General Information
Drug ID
D07OSS
Former ID
DIB006592
Drug Name
9cUAB-30
Synonyms
UAB-112; UAB-20; UAB-30; UAB-75; UAB-76; UAB-8; Retinoic acid analogs (cancer), University of Alabama; (9Z)-UAB-30
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 1 [528795]
Company
University of Alabama at Birmingham
Canonical SMILES
C\1(=C\C(=C/C=C/C(=C/C(=O)O)/C)\C)/c2c(CCC1)cccc2
CAS Number
CAS 205252-59-1
Target and Pathway
Target(s) Retinoic acid receptor RXR-gamma Target Info Modulator [528795]
KEGG Pathway PPAR signaling pathway
Thyroid hormone signaling pathway
Adipocytokine signaling pathway
Pathways in cancer
Transcriptional misregulation in cancer
Thyroid cancer
Small cell lung cancer
Non-small cell lung cancer
Pathway Interaction Database Regulation of Androgen receptor activity
RXR and RAR heterodimerization with other nuclear receptor
Retinoic acid receptors-mediated signaling
a6b1 and a6b4 Integrin signaling
Reactome Nuclear Receptor transcription pathway
WikiPathways Vitamin A and Carotenoid Metabolism
Adipogenesis
Nuclear Receptors
References
Ref 528795In vitro metabolic characterization, phenotyping, and kinetic studies of 9cUAB30, a retinoid X receptor-specific retinoid. Drug Metab Dispos. 2007 Jul;35(7):1157-64. Epub 2007 Apr 19.
Ref 528795In vitro metabolic characterization, phenotyping, and kinetic studies of 9cUAB30, a retinoid X receptor-specific retinoid. Drug Metab Dispos. 2007 Jul;35(7):1157-64. Epub 2007 Apr 19.

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