Drug Information

Drug General Information
Drug ID
D07OSA
Former ID
DIB020864
Drug Name
RS67506
Synonyms
RS-67506
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540206]
Formula
C18H28ClN3O4S
InChI
InChI=1S/C18H28ClN3O4S/c1-26-18-12-16(20)15(19)11-14(18)17(23)4-3-13-5-8-22(9-6-13)10-7-21-27(2,24)25/h11-13,21H,3-10,20H2,1-2H3
InChIKey
UATDVRSFFGFTAI-UHFFFAOYSA-N
PubChem Compound ID
133076
PubChem Substance ID
7361806, 10243292, 11113837, 26752011, 29311077, 47285926, 47359962, 47434911, 47657156, 80068056, 85209376, 85788124, 103285932, 104378942, 129341585, 136351051, 143031230, 178100287, 223532831, 225035564, 226857715
Target and Pathway
Target(s) 5-hydroxytryptamine 4 receptor Target Info Agonist [534265]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT4 type receptor mediated signaling pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 540206(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3230).
Ref 534265Peripheral 5-HT4 receptors. FASEB J. 1996 Oct;10(12):1398-407.

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