Drug Information

Drug General Information
Drug ID
D07KHR
Former ID
DIB006110
Drug Name
PSMA-VRP
Synonyms
Alphavirus vector vaccine (prostate cancer), Progenics/Cytogen; PSMA antigen vaccine (prostate cancer), PSMA Co LLC/AlphaVax;PSMA viral vector vaccine (prostate cancer), PSMA Co LLC/AlphaVax; PSMA viral vector vaccine (prostate cancer), Progenics/CYTOGEN; PSMA antigen vaccine (prostate cancer), CYTOGEN/Progenics/AlphaVax
Drug Type
Vaccine
Indication Prostate cancer [ICD9: 185; ICD10:C61] Phase 1 [547026]
Company
Alphavax
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info [532158]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 547026Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012200)
Ref 532158A phase I dose escalation trial of vaccine replicon particles (VRP) expressing prostate-specific membrane antigen (PSMA) in subjects with prostate cancer. Vaccine. 2013 Jan 30;31(6):943-9.

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