Drug Information

Drug General Information
Drug ID
D07JOS
Former ID
DIB013411
Drug Name
NS-004
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Terminated [467608], [534399]
Company
NeuroSearch A/S
Formula
C14H8ClF3N2O2
InChI
InChI=1S/C14H8ClF3N2O2/c15-8-2-4-12(21)11(6-8)20-10-3-1-7(14(16,17)18)5-9(10)19-13(20)22/h1-6,21H,(H,19,22)
InChIKey
WYLYBVMNGZOYOH-UHFFFAOYSA-N
CAS Number
CAS 141797-92-4
PubChem Compound ID
5311330
PubChem Substance ID
7980178, 11056441, 14899714, 39341020, 50184218, 57359436, 103505908, 114155847, 125503228, 127350407, 129652595, 134964133, 140976117, 162118530, 178101088, 224957577, 229149530, 234371917
Target and Pathway
Target(s) Potassium channel Target Info Opener [534399]
References
Ref 467608(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4271).
Ref 534399Effects of K+ channel inhibitors and antagonists on NS-004 evoked relaxations in guinea-pig isolated trachea. Fundam Clin Pharmacol. 1997;11(1):78-82.
Ref 534399Effects of K+ channel inhibitors and antagonists on NS-004 evoked relaxations in guinea-pig isolated trachea. Fundam Clin Pharmacol. 1997;11(1):78-82.

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