Drug Information

Drug General Information
Drug ID
D06YOD
Former ID
DIB015948
Drug Name
ZD-7717
Synonyms
ICI D7717
Indication Asthma [ICD10:J45] Terminated [546302]
Company
Zeneca Group plc
Canonical SMILES
N1(c2c(OCC1=O)cc(Sc1cc(C3(CCOCC3)OC)cc(c1)F)cc2)C
CAS Number
CAS 187112-64-7
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Modulator [550946]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 546302Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007338)
Ref 550946CA patent application no. 445634, Acne treatment comprising lipoxygenase inhibitors.

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