Drug Information

Drug General Information
Drug ID
D06WSQ
Former ID
DIB001408
Drug Name
AWD-140-190
Synonyms
AWD-12-151
Indication Epileptic seizures [ICD9: 345.9, 780.3; ICD10:G40, P90, R56] Discontinued in Phase 1 [545957]
Company
ASTA Medica AG
Canonical SMILES
c1(c(c(c[nH]1)c1ccc(cc1)Br)N1CCOCC1)C(=O)OC
CAS Number
CAS 135548-66-2
Target and Pathway
Target(s) Sodium channel Target Info Modulator [534534]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 545957Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005495)
Ref 534534Effects of AWD 140-190 on stimulus-induced field potentials and on different patterns of epileptiform activity induced by low calcium or low magnesium in rat entorhinal cortex hippocampal slices. Epilepsy Res. 1997 Dec;29(1):59-69.

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