Drug Information

Drug General Information
Drug ID
D06SRX
Former ID
DIB016932
Drug Name
MDA-19
Synonyms
Cannabinoid CB2 agonist (neuropathic pain), MD Anderson Cancer Center
Drug Type
Small molecular drug
Indication Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] Investigative [543878]
Company
MD Anderson Cancer Center
Formula
C21H23N3O2
Canonical SMILES
C\1(=N/NC(=O)c2ccccc2)/C(=O)N(c2c1cccc2)CCCCCC
PubChem Compound ID
25034599
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Agonist [543878]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543878(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).
Ref 543878(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).

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