Drug Information

Drug General Information
Drug ID
D06QZL
Former ID
DCL000864
Drug Name
Lerisetron
Synonyms
Lerisetron[inn]; 1-benzyl-2-piperazin-1-ylbenzimidazole
Drug Type
Small molecular drug
Indication Nausea; Vomiting; Testicular germ cell tumor; Emesis [ICD9: 140-199, 183, 186, 210-229, 220, 222.0, 787, 787.0; ICD10:C00-C75, C56, C62, C7A, C7B, D10-D36, D27, D29.2, D3A, R11] Phase 3 [536188]
Company
FAES Farma
Formula
C18H20N4
Canonical SMILES
C1CN(CCN1)C2=NC3=CC=CC=C3N2CC4=CC=CC=C4
InChI
1S/C18H20N4/c1-2-6-15(7-3-1)14-22-17-9-5-4-8-16(17)20-18(22)21-12-10-19-11-13-21/h1-9,19H,10-14H2
InChIKey
PWWDCRQZITYKDV-UHFFFAOYSA-N
CAS Number
CAS 143257-98-1
PubChem Compound ID
65997
PubChem Substance ID
8190090, 14873434, 43122719, 50404050, 57315883, 103245517, 103999419, 104335210, 117523497, 123206385, 125670572, 128979884, 134338727, 134339323, 135024019, 137249402, 139722277, 152097134, 162107001, 172867306, 179149921, 198990772, 223109624, 223824232, 226508144, 241035426
Target and Pathway
Target(s) 5-Hydroxytryptamine 3 receptor Target Info Antagonist [536188]
References
Ref 536188Emerging drugs for chemotherapy-induced emesis. Expert Opin Emerg Drugs. 2006 Mar;11(1):137-51.
Ref 536188Emerging drugs for chemotherapy-induced emesis. Expert Opin Emerg Drugs. 2006 Mar;11(1):137-51.

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