Drug Information

Drug General Information
Drug ID
D06NSS
Former ID
DAP000819
Drug Name
Cromoglicate
Synonyms
Crolom (TN); Intal (TN); Nasalcrom (TN); Opticrom (TN); Optrex Allergy (TN); Prevalin (TN); Rynacrom (TN)
Drug Type
Small molecular drug
Indication Allergic rhinitis [ICD9: 472.0, 477, 995.3; ICD10:J00, J30, J31.0, T78.4] Terminated [536429]
Therapeutic Class
Antiasthmatic Agents
Company
Zambon Group
Formula
C23H16O11
Canonical SMILES
C1=CC2=C(C(=C1)OCC(COC3=CC4=C(C=C3)OC(=CC4=O)C(=O)O)O)C<br />(=O)C=C(O2)C(=O)O
InChI
1S/C23H16O11/c24-11(9-31-12-4-5-16-13(6-12)14(25)7-19(33-16)22(27)28)10-32-17-2-1-3-18-21(17)15(26)8-20(34-18)23(29)30/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30)
InChIKey
FSINDHDHRQZTPH-UHFFFAOYSA-N
CAS Number
CAS 16110-51-3
PubChem Compound ID
27686
PubChem Substance ID
7783792, 34670188, 49889116, 57310496, 76877480, 104300670, 124899350, 127892624, 134338100, 160964339, 164786741, 236443228
ChEBI ID
ChEBI:3922
SuperDrug ATC ID
A07EB01
SuperDrug CAS ID
cas=016110513
Target and Pathway
Target(s) Heat shock protein HSP90 Target Info Inhibitor [535743]
References
Ref 536429Sodium cromoglicate: an ineffective drug or meta-analysis misused? Pharm Stat. 2007 Apr-Jun;6(2):123-37.
Ref 535743Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox. Biochem J. 2003 Sep 1;374(Pt 2):433-41.

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