Drug Information

Drug General Information
Drug ID
D06NAM
Former ID
DIB020586
Drug Name
O-1602
Synonyms
O 1602
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540919]
Formula
C17H22O2
InChI
InChI=1S/C17H22O2/c1-10(2)14-6-5-11(3)7-15(14)17-12(4)8-13(18)9-16(17)19/h7-9,14-15,18-19H,1,5-6H2,2-4H3/t14-,15+/m0/s1
InChIKey
KDZOUSULXZNDJH-LSDHHAIUSA-N
PubChem Compound ID
45073499
PubChem Substance ID
91746623, 104547812, 120157169, 141022818, 163122268, 170481113, 174811360, 178102168, 204362660, 229751276, 241070410, 241376130, 243841760, 252156798, 252457778
Target and Pathway
Target(s) GPR18 Target Info Agonist [531489]
G-protein coupled receptor 55 Target Info Agonist [531264]
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540919(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5525).
Ref 531264International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB??and CB?? Pharmacol Rev. 2010 Dec;62(4):588-631.
Ref 531489Delta(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. Br J Pharmacol. 2012 Apr;165(8):2414-24.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.