Drug Information

Drug General Information
Drug ID
D06FWM
Former ID
DNC007816
Drug Name
N-(3-(1H-indol-4-yloxy)propyl)cyclohexanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529018]
Formula
C17H24N2O
Canonical SMILES
C1CCC(CC1)NCCCOC2=CC=CC3=C2C=CN3
InChI
1S/C17H24N2O/c1-2-6-14(7-3-1)18-11-5-13-20-17-9-4-8-16-15(17)10-12-19-16/h4,8-10,12,14,18-19H,1-3,5-7,11,13H2
InChIKey
QVATUGJQJMJAPA-UHFFFAOYSA-N
PubChem Compound ID
44433247
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [529018]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529018Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.
Ref 529018Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.

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