Drug Information

Drug General Information
Drug ID
D06EMW
Former ID
DCL000485
Drug Name
AZD8566
Indication Chronic obstructive pulmonary disease; Rheumatoid arthritis [ICD9: 460-519, 490-492, 494-496, 710-719, 714; ICD10:J00-J99, J40-J44, J47, M00-M25, M05-M06] Discontinued in Phase 1 [548691]
Company
AstraZeneca
Target and Pathway
Target(s) C-C chemokinereceptor type 5 Target Info Antagonist [550288]
KEGG Pathway Cytokine-cytokine receptor interaction
Chemokine signaling pathway
Endocytosis
Toxoplasmosis
Viral carcinogenesis
NetPath Pathway TSLP Signaling Pathway
TCR Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database IL12-mediated signaling events
Reactome Binding and entry of HIV virion
Chemokine receptors bind chemokines
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
HIV Life Cycle
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 548691Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027710)
Ref 550288Clinical pipeline report, company report or official report of AstraZeneca (2009).

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