Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06CJP
|
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| Former ID |
DNC007350
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| Drug Name |
4-chloro-1-guanidino-7-isoquinolinesulphonamide
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528796] | ||
| Formula |
C10H10ClN5O2S
|
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| Canonical SMILES |
C1=CC2=C(C=C1S(=O)(=O)N)C(=NC=C2Cl)N=C(N)N
|
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| InChI |
1S/C10H10ClN5O2S/c11-8-4-15-9(16-10(12)13)7-3-5(19(14,17)18)1-2-6(7)8/h1-4H,(H2,14,17,18)(H4,12,13,15,16)
|
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| InChIKey |
FXVHAOFNNRNCRJ-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Urokinase-type plasminogen activator | Target Info | Inhibitor | [528796] | |
| NetPath Pathway | IL2 Signaling Pathway | ||||
| EGFR1 Signaling Pathway | |||||
| Pathway Interaction Database | Beta1 integrin cell surface interactions | ||||
| E2F transcription factor network | |||||
| Beta3 integrin cell surface interactions | |||||
| Osteopontin-mediated events | |||||
| Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||||
| amb2 Integrin signaling | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| Beta2 integrin cell surface interactions | |||||
| Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||||
| Beta5 beta6 beta7 and beta8 integrin cell surface interactions | |||||
| FGF signaling pathway | |||||
| Reactome | Dissolution of Fibrin Clot | ||||
| References | |||||
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