Drug Information

Drug General Information
Drug ID
D05ZGQ
Drug Name
Dexchlorpheniramine Maleate
Synonyms
Dexchlorpheniramine Maleate; Polaramine
Drug Type
Small molecular drug
Indication Rhinitis; Urticaria; Allergy [ICD10:J00, J30, J31.0, L50, T78.4] Approved [551871]
Company
Schering Corp Sub Schering Plough Corp
Formula
C20H23ClN2O4
PubChem Compound ID
5281070
Target and Pathway
Target(s) Histamine H1 receptor Target Info Modulator [556264]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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