Drug Information

Drug General Information
Drug ID
D05SKE
Former ID
DNC006460
Drug Name
6-bromo-3-(pyridin-4-yl)-1H-indole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528040]
Formula
C13H9BrN2
Canonical SMILES
C1=CC2=C(C=C1Br)NC=C2C3=CC=NC=C3
InChI
1S/C13H9BrN2/c14-10-1-2-11-12(8-16-13(11)7-10)9-3-5-15-6-4-9/h1-8,16H
InChIKey
KLYDZCDPTMADJL-UHFFFAOYSA-N
PubChem Compound ID
44410796
Target and Pathway
Target(s) Inosine-5'-monophosphate dehydrogenase 2 Target Info Inhibitor [528040]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Guanosine nucleotides de novo biosynthesis
Superpathway of purine nucleotide salvage
Purine nucleotides de novo biosynthesis
Guanosine ribonucleotides de novo biosynthesis
KEGG Pathway Purine metabolism
Drug metabolism - other enzymes
Metabolic pathways
PANTHER Pathway De novo purine biosynthesis
Reactome Purine ribonucleoside monophosphate biosynthesis
References
Ref 528040Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. Epub 2006 Feb 17.Low molecular weight indole fragments as IMPDH inhibitors.
Ref 528040Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. Epub 2006 Feb 17.Low molecular weight indole fragments as IMPDH inhibitors.

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