TTD | Drug: D05PQF

Drug General Information
Drug ID	D05PQF
Former ID	DIB011287
Drug Name	ONO-4127Na
Synonyms	Allergic rhinitis agent, Ono
Indication	Allergic rhinitis [ICD9: 472.0, 477, 995.3; ICD10:J00, J30, J31.0, T78.4]		Discontinued in Phase 1	[547738]
Company	Ono Pharmaceutical Co Ltd
Target and Pathway
Target(s)	Prostaglandin D2 receptor	Target Info	Antagonist	[531930]
KEGG Pathway	Neuroactive ligand-receptor interaction
Pathway Interaction Database	Thromboxane A2 receptor signaling
PathWhiz Pathway	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2
Reactome	Prostanoid ligand receptors
Reactome	G alpha (s) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 547738	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018932)
Ref 531930	Sleep-wake regulation by prostaglandin D2 and adenosine. Brain Nerve. 2012 Jun;64(6):621-8.

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Drug Information