Drug Information

Drug General Information
Drug ID
D05MOZ
Former ID
DNCL002205
Drug Name
G-202
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 2 [524201]
Company
GenSpera
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info Inhibitor [550453]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 524201ClinicalTrials.gov (NCT01777594) Study of G-202 as Second-Line Therapy Following Sorafenib in Hepatocellular Carcinoma. U.S. National Institutes of Health.
Ref 550453National Cancer Institute Drug Dictionary (drug id 666090).

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