Drug Information

Drug General Information
Drug ID
D05LRD
Former ID
DNCL001932
Drug Name
BMS-933043
Indication Psychiatric disorder [ICD9: 290-319; ICD10:F01-F99] Phase 1 [523918]
Company
Bristol-Myers Squibb
Target and Pathway
Target(s) Neuronal acetylcholine receptor protein, alpha-7 chain Target Info Modulator [550057]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Nicotine addiction
Chemical carcinogenesis
PANTHER Pathway Alzheimer disease-amyloid secretase pathway
Nicotinic acetylcholine receptor signaling pathway
Reactome Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 523918ClinicalTrials.gov (NCT01605994) Multiple Ascending-Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BMS-933043 in Healthy Subjects. U.S. National Institutes of Health.
Ref 550057Clinical pipeline report, company report or official report of Phrma.org Alzheimers 2012.

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