Drug Information

Drug General Information
Drug ID
D05LQD
Former ID
DNC006331
Drug Name
3-hydroxy-4,10-dimethyl-6H-benzo[c]chromen-6-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527966]
Formula
C15H12O3
Canonical SMILES
CC1=CC=CC2=C1C3=C(C(=C(C=C3)O)C)OC2=O
InChI
1S/C15H12O3/c1-8-4-3-5-11-13(8)10-6-7-12(16)9(2)14(10)18-15(11)17/h3-7,16H,1-2H3
InChIKey
PSZUCXJKMVSZSN-UHFFFAOYSA-N
PubChem Compound ID
10082995
Target and Pathway
Target(s) Estrogen receptor beta Target Info Inhibitor [527966]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathway
Pathway Interaction Database Plasma membrane estrogen receptor signaling
Validated nuclear estrogen receptor beta network
Validated nuclear estrogen receptor alpha network
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Ovarian Infertility Genes
Integrated Pancreatic Cancer Pathway
Nuclear Receptors
References
Ref 527966Bioorg Med Chem Lett. 2006 Mar 15;16(6):1468-72. Epub 2006 Jan 18.6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.
Ref 527966Bioorg Med Chem Lett. 2006 Mar 15;16(6):1468-72. Epub 2006 Jan 18.6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.

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