Drug Information

Drug General Information
Drug ID
D05IHR
Former ID
DNC012812
Drug Name
9-Phenyl-2,3-dihydro-1H-indeno[2,1-c]pyridine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525803]
Formula
C18H15N
Canonical SMILES
C1C=C2C(=C(C3=CC=CC=C23)C4=CC=CC=C4)CN1
InChI
1S/C18H15N/c1-2-6-13(7-3-1)18-16-9-5-4-8-14(16)15-10-11-19-12-17(15)18/h1-10,19H,11-12H2
InChIKey
KIUIXTNMEMKNGK-UHFFFAOYSA-N
PubChem Compound ID
15830914
Target and Pathway
Target(s) Histamine H1 receptor Target Info Inhibitor [525803]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 525803Bioorg Med Chem Lett. 2000 Jun 5;10(11):1277-9.Conformationally-restricted ligands for the histamine H1 receptor.
Ref 525803Bioorg Med Chem Lett. 2000 Jun 5;10(11):1277-9.Conformationally-restricted ligands for the histamine H1 receptor.

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