Drug Information

Drug General Information
Drug ID
D05HOS
Former ID
DNC002837
Drug Name
Hydroxyaminovaline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Formula
C5H12N2O2
Canonical SMILES
CC(C)C(C(=O)NO)N
InChI
1S/C5H12N2O2/c1-3(2)4(6)5(8)7-9/h3-4,9H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
InChIKey
USSBBYRBOWZYSB-SCSAIBSYSA-N
PubChem Compound ID
444599
PubChem Substance ID
838552, 7888071, 26703454, 36887565, 46508565, 51762563, 104632470, 129415060, 132631049, 137185103, 160965872, 162692513, 228616832
Target and Pathway
Target(s) Collagenase 3 Target Info Inhibitor [551393]
Stromelysin-1 Target Info Inhibitor [551393]
KEGG Pathway TNF signaling pathway
Transcriptional misregulation in cancer
Rheumatoid arthritis
NetPath Pathway IL1 Signaling PathwayNetPath_13:IL1 Signaling Pathway
IL4 Signaling Pathway
PANTHER Pathway Alzheimer disease-presenilin pathway
Plasminogen activating cascadeP00050:Plasminogen activating cascade
CCKR signaling map ST
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signalingajdiss_2pathway:Posttranslational regulation of adherens junction stability and dissassembly
p75(NTR)-mediated signaling
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Assembly of collagen fibrils and other multimeric structuresR-HSA-1442490:Collagen degradation
Assembly of collagen fibrils and other multimeric structures
EGFR Transactivation by Gastrin
WikiPathways Endochondral Ossification
Activation of Matrix Metalloproteinases
Oncostatin M Signaling Pathway
AGE/RAGE pathway
Matrix MetalloproteinasesWP2769:Activation of Matrix Metalloproteinases
Gastrin-CREB signalling pathway via PKC and MAPK
Matrix Metalloproteinases
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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