Drug Information

Drug General Information
Drug ID
D05DXT
Former ID
DIB016833
Drug Name
XEN-D0103
Synonyms
KCNA voltage-gated potassium channel-5 inhibitor (atrial fibrillation), Xention
Indication Atrial fibrillation [ICD9: 272, 427.31; ICD10:E78, I48] Phase 1 [525123]
Company
Xention Ltd
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily A member 5 Target Info Inhibitor [543876]
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channels
WikiPathways Potassium Channels
References
Ref 525123ClinicalTrials.gov (NCT02390258) Fed-Fasted, Single and Multiple Ascending Dose Trial of XEN-D0103. U.S. National Institutes of Health.
Ref 543876(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 542).

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