Drug Information

Drug General Information
Drug ID
D05BYD
Former ID
DIB018714
Drug Name
A-304121
Synonyms
A304121; A 304121
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538773]
Formula
C20H29N3O3
InChI
InChI=1S/C20H29N3O3/c1-15(21)20(25)23-12-10-22(11-13-23)9-2-14-26-18-7-5-17(6-8-18)19(24)16-3-4-16/h5-8,15-16H,2-4,9-14,21H2,1H3/t15-/m1/s1
InChIKey
KPXVCGPCRXEDLT-OAHLLOKOSA-N
PubChem Compound ID
9906860
PubChem Substance ID
14876740, 15399154, 24188159, 45978524, 50075730, 74457016, 103254726, 104029201, 135327431, 135649871, 198934803, 232881500
Target and Pathway
Target(s) Histamine H3 receptor Target Info Antagonist [527161]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 538773(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1258).
Ref 527161Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist. Biochem Pharmacol. 2004 Sep 1;68(5):933-45.

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