Drug Information

Drug General Information
Drug ID
D04XZE
Former ID
DNC001582
Drug Name
NS-7
Drug Type
Small molecular drug
Indication Nerve injury [ICD10:T14.4] Phase 2 [525754]
Therapeutic Class
Analgesics
Formula
C19H29N3O4S2
Canonical SMILES
CC1=C(C=C2C(=C1)CC(NS2(=O)=O)C3CCCC3)S(=O)(=O)N4CCN(CC4<br />)C
InChI
1S/C19H29N3O4S2/c1-14-11-16-12-17(15-5-3-4-6-15)20-27(23,24)19(16)13-18(14)28(25,26)22-9-7-21(2)8-10-22/h11,13,15,17,20H,3-10,12H2,1-2H3/t17-/m1/s1
InChIKey
KQAGZLQCEURCKJ-QGZVFWFLSA-N
PubChem Compound ID
44129631
PubChem Substance ID
84982006, 99444776, 160969354
Target and Pathway
Target(s) Sodium channel Target Info Modulator [525754]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 525754Preferential inhibition by a novel Na(+)/Ca(2+) channel blocker NS-7 of severe to mild hypoxic injury in rat cerebrocortical slices: A possible involvement of a highly voltage-dependent blockade of Ca(2+) channel. J Pharmacol Exp Ther. 2000 May;293(2):522-9.
Ref 525754Preferential inhibition by a novel Na(+)/Ca(2+) channel blocker NS-7 of severe to mild hypoxic injury in rat cerebrocortical slices: A possible involvement of a highly voltage-dependent blockade of Ca(2+) channel. J Pharmacol Exp Ther. 2000 May;293(2):522-9.

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