Drug Information

Drug General Information
Drug ID
D04WIA
Former ID
DNC011956
Drug Name
2-Pyridin-2-yl-6H-pyrazolo[1,5-c]quinazolin-5-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534157]
Formula
C15H10N4O
Canonical SMILES
C1=CC=NC(=C1)C2=CC3=C4C=CC=CC4=NC(=O)N3N2
InChI
1S/C15H10N4O/c20-15-17-11-6-2-1-5-10(11)14-9-13(18-19(14)15)12-7-3-4-8-16-12/h1-9,18H
InChIKey
LPUOGVWEOKCYCJ-UHFFFAOYSA-N
PubChem Compound ID
10587546
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Inhibitor [534157]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [534157]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 534157J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.
Ref 534157J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.

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