Drug Information

Drug General Information
Drug ID
D04UUT
Former ID
DNC011958
Drug Name
2-Furan-2-yl-6H-pyrazolo[1,5-c]quinazolin-5-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534157]
Formula
C14H9N3O2
Canonical SMILES
C1=CC2=C3C=C(NN3C(=O)N=C2C=C1)C4=CC=CO4
InChI
1S/C14H9N3O2/c18-14-15-10-5-2-1-4-9(10)12-8-11(16-17(12)14)13-6-3-7-19-13/h1-8,16H
InChIKey
CURSNYMOHJSYQS-UHFFFAOYSA-N
PubChem Compound ID
10467327
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Inhibitor [534157]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [534157]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 534157J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.
Ref 534157J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.

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