Drug Information

Drug General Information
Drug ID
D04TZR
Drug Name
ICI-204448
Synonyms
121264-04-8; ICI-204448
Drug Type
Small molecular drug
Indication Unspecified Investigative [1560458]
Formula
C23H26Cl2N2O4
PubChem Compound ID
3683
Target and Pathway
Target(s) Kappa-type opioid receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Opioid prodynorphin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 1560458ICI 204448: a kappa-opioid agonist with limited access to the CNS.

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