Drug Information

Drug General Information
Drug ID
D04SPM
Former ID
DIB018327
Drug Name
[3H]LY278584
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540682]
Formula
C17H22N4O
InChI
InChI=1S/C17H22N4O/c1-20-12-7-8-13(20)10-11(9-12)18-17(22)16-14-5-3-4-6-15(14)21(2)19-16/h3-6,11-13H,7-10H2,1-2H3,(H,18,22)/t11?,12-,13+
InChIKey
DDHAJFBBJWHSBR-YHWZYXNKSA-N
PubChem Compound ID
5311254
Target and Pathway
Target(s) 5-hydroxytryptamine receptor 3A Target Info Antagonist [534033]
KEGG Pathway Serotonergic synapse
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway 5HT3 type receptor mediated signaling pathway
Reactome Ligand-gated ion channel transport
WikiPathways SIDS Susceptibility Pathways
Iron uptake and transport
References
Ref 540682(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4087).
Ref 534033Pharmacological and regional characterization of [3H]LY278584 binding sites in human brain. J Neurochem. 1993 Feb;60(2):730-7.

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