Drug Information

Drug General Information
Drug ID
D04QZD
Former ID
DNC000619
Drug Name
Eslicarbazepine
Synonyms
Aptiom; BIA 2-093; ESL; Exalief; SEP-0002093; SEP-2093; Stedesa; Zebinix
Drug Type
Small molecular drug
Indication Seizures [ICD9: 345.9, 780.3; ICD10:G40, P90, R56] Approved [532651], [542371]
Therapeutic Class
Neurology Agents
Formula
C15H14N2O2
InChI
InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m0/s1
InChIKey
BMPDWHIDQYTSHX-AWEZNQCLSA-N
CAS Number
CAS 236395-14-5
PubChem Compound ID
9881504
PubChem Substance ID
14847818, 24169052, 45628457, 61013447, 74832373, 96025895, 103293530, 118310966, 126665681, 127537462, 135253067, 143479487, 162188093, 163124654, 163696949, 164230651, 164763126, 172860101, 175266523, 178103922, 198977350, 204360581, 219401211, 223533430, 223653619, 224675811, 226744763, 249855365, 250218635, 252077440, 252429028
SuperDrug ATC ID
N03AF04
Target and Pathway
Target(s) Sodium channel Target Info Blocker [536934]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 5326512013 FDA drug approvals. Nat Rev Drug Discov. 2014 Feb;13(2):85-9.
Ref 542371(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7350).
Ref 536934Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan;83(1):1-43. Epub 2008 Nov 12.

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