Drug Information

Drug General Information
Drug ID
D04PGO
Former ID
DIB005787
Drug Name
MDL-28133A
Drug Type
Small molecular drug
Indication Thromboembolism [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] Terminated [545319]
Company
Hoechst Marion Roussel Inc
Formula
C21H24ClFN2O4S
Canonical SMILES
S(=O)(=O)(Nc1ccc(C(=O)C2CCN(CC(=O)c3ccc(cc3)F)CC2)cc1)C<br />.Cl
CAS Number
CAS 136861-96-6
PubChem Compound ID
132001
Target and Pathway
Target(s) 5-HT 2 receptor Target Info Modulator [533621]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
References
Ref 545319Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002814)
Ref 533621Effects of MDL 28,133A, a 5-HT2 receptor antagonist, on platelet aggregation and coronary thrombosis in dogs. J Cardiovasc Pharmacol. 1994 Nov;24(5):761-72.

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