Drug Information

Drug General Information
Drug ID
D04KDB
Former ID
DNC004499
Drug Name
6-Imidazol-1-yl-3,4-dihydro-1H-quinolin-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526726]
Formula
C12H11N3O
Canonical SMILES
C1CC(=O)NC2=C1C=C(C=C2)N3C=CN=C3
InChI
1S/C12H11N3O/c16-12-4-1-9-7-10(2-3-11(9)14-12)15-6-5-13-8-15/h2-3,5-8H,1,4H2,(H,14,16)
InChIKey
BDMKPUAZENLRDY-UHFFFAOYSA-N
PubChem Compound ID
13885278
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase A Target Info Inhibitor [526726]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 526726J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
Ref 526726J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.

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