Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04FQA
|
||||
| Former ID |
DNC000070
|
||||
| Drug Name |
4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone
|
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| Indication | Discovery agent | Investigative | [534957] | ||
| Target and Pathway | |||||
| Target(s) | Type-1 angiotensin II receptor | Target Info | Antagonist | [534957] | |
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Arf6 trafficking events | ||||
| Arf6 signaling events | |||||
| Angiopoietin receptor Tie2-mediated signaling | |||||
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| Muscle/Heart Contraction | |||||
| References | |||||
| Ref 534957 | Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies. J Med Chem. 2000 Feb 10;43(3):351-60. | ||||
| Ref 534957 | Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies. J Med Chem. 2000 Feb 10;43(3):351-60. | ||||
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