Drug Information

Drug General Information
Drug ID
D04DMQ
Former ID
DIB010695
Drug Name
Fabesetron
Synonyms
FK-1052
Drug Type
Small molecular drug
Indication Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] Discontinued in Phase 2 [544894]
Company
Fujisawa Pharmaceutical Co Ltd
Formula
C18H19N3O
Canonical SMILES
n12c(c(c3c2cccc3)C)CC[C@@H](C1=O)Cc1c(nc[nH]1)C.Cl
PubChem Compound ID
208947
Target and Pathway
Target(s) 5-hydroxytryptamine 4 receptor Target Info Modulator
5-HT 3 receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT4 type receptor mediated signaling pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 544894Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001434)

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.