Drug Information

Drug General Information
Drug ID
D04AUM
Former ID
DNC013414
Drug Name
AM-1710
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529170]
Formula
C23H28O4
Canonical SMILES
CCCCCCC(C)(C)C1=CC2=C(C(=C1)O)C3=C(C=CC(=C3)OC)C(=O)O2
InChI
1S/C23H28O4/c1-5-6-7-8-11-23(2,3)15-12-19(24)21-18-14-16(26-4)9-10-17(18)22(25)27-20(21)13-15/h9-10,12-14,24H,5-8,11H2,1-4H3
InChIKey
ZAIKPEWFCSQNQB-UHFFFAOYSA-N
PubChem Compound ID
11268660
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Inhibitor [529170]
Cannabinoid receptor 1 Target Info Inhibitor [529170]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
BDNF signaling pathway
GPCR downstream signaling
GPCRs, Other
References
Ref 529170J Med Chem. 2007 Dec 27;50(26):6493-500. Epub 2007 Nov 27.Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.
Ref 529170J Med Chem. 2007 Dec 27;50(26):6493-500. Epub 2007 Nov 27.Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.

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