Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04APY
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| Former ID |
DIB008912
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| Drug Name |
KC-11404
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| Indication | Asthma [ICD10:J45] | Terminated | [533776] | ||
| Company |
Solvay Deutschland GmbH
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| Canonical SMILES |
n12c(c(c3c1c(cc(c3)O)CCC2CCCC)CCN1CCN(c2nccc(c2)C)CC1)C
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| CAS Number |
CAS 148490-22-6
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| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Modulator | [533776] | |
| Platelet-activating factor receptor | Target Info | Modulator | [533776] | ||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| References | |||||
| Ref 533776 | Synthesis, structure-activity relationships, and pharmacological evaluation of pyrrolo[3,2,1-ij]quinoline derivatives: potent histamine and platelet activating factor antagonism and 5-lipoxygenase inhibitory properties. Potential therapeutic application in asthma. J Med Chem. 1995 Feb 17;38(4):669-85. | ||||
| Ref 533776 | Synthesis, structure-activity relationships, and pharmacological evaluation of pyrrolo[3,2,1-ij]quinoline derivatives: potent histamine and platelet activating factor antagonism and 5-lipoxygenase inhibitory properties. Potential therapeutic application in asthma. J Med Chem. 1995 Feb 17;38(4):669-85. | ||||
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